OSU:pro
Dr. Kenneth John McLaughlin
The Research Institute at Nationwide Children's Hospital
700 Children's Drive, W411
Columbus, OH 43205
Phone: (614) 355-3484
Fax: (614) 722-2817
Email: mclaughlin.261@osu.edu
Current OSU Appointment
Associate Professor, Pediatrics
Abstracts and Short Entries
McLaughlin KJ; Walker SK; Davies L; Mawson B; Seamark RF. 1989. Culture and manipulation of early goat embryos [Abstract]. Theriogenology. Vol. 31: 227. [Peer Reviewed] (Published)
McLaughlin KJ; Pugh AP; Logan K; Tervit HR. 1991. Assessment of oocyte source for ovine nuclear transfer [Abstract]. Theriogenology. Vol. 35: 187. (Published)
McLaughlin KJ; McLean DM; Stevens G; Bartsch BD; Seamark RF. 1992. In vitro culture in the production of bovine nuclear transplant embryos [Abstract]. Theriogenology. Vol. 37: 231. [Peer Reviewed] (Published)
McLaughlin, KJ. 1993. Production of tetraploid embryos by electrofusion [Abstract]. Methods in Enzymology. Vol. 225: Associated Press: 919-930. [Peer Reviewed] (Published)
Boiani M; Scholer HR; McLaughlin KJ. 2002. Assessing culture conditions for clone embryo development in the mouse [Abstract]. Theriogenology. Vol. 57, no. 1: 3. [Peer Reviewed] (Published)
Eckardt S; Boiani M; Friez MK; Scholer HR; McLaughlin KJ. 2002. Mouse clone blastocytes: Gene expression and outgrowth formation [Abstract]. Theriogenology. Vol. 57, no. 1: 411. [Peer Reviewed] (Published)
Eckardt S; Leu NA; McLaughlin KJ. 2003. Reprogramming of somatic cell nuclei in cleavage stage blastomeres [Abstract]. Theriogenology. Vol. 59, no. 1: 249. [Peer Reviewed] (Published)
Eckardt S; Leu NA; McLaughlin KJ. 2004. Developmental potential of clone cells in murine clone-fertilized aggregation chimeras. [Abstract]. 16 ed. Vol. 1-2: Reproduction, Fertility and Development: 141. [Peer Reviewed] (Published)
Kurosaka S; Eckardt S; Friez MK; Leu NA; Reinbold R; McLaughlin KJ. 2004. Spatial expression of Oct4 is normally regulated in preimplantation stage bovine somatic cell clones [Abstract]. Reproduction, Fertility and Development. Vol. 16, no. 1-2: 147. [Peer Reviewed] (Published)
Kurosaka S; McLaughlin KJ. 2005. DNA synthesis, preimplantation development and Oct4 expression of bovine clones reconstructed with oocytes preactivated or enucleated after spindle disassembly. [Abstract]. no. 17: Reproduction, Fertility and Development: 171. [Peer Reviewed] (Published)
Kurosaka S; Leu NA; McLaughlin KJ. 2006. Aggregation reduces the variation of gene expression levels in bovine clones. [Abstract]. no. 18: Reproduction, Fertility and Development: 134. [Peer Reviewed] (Published)
Kurosaka S; Ealy AD; McLaughlin KJ. 2007. No beneficial effect of aggregation on interferon tau activity in bovine clone outgrowths. [Abstract]. Vol. 1, no. 19: Reproduction, Fertility and Development: 146. [Peer Reviewed] (Published)
Eckardt S; McLaughlin KJ. 2008. Transplantation of chimeric fetal liver to study hematopoietic development of mutant ES cells or embryonic lethal mouse mutants [Abstract]. Methods in Molecular Biology. Vol. 430: 195-211. [Peer Reviewed] (Published)
Chapters In Books
Eckardt, S; Kurosaka S; McLaughlin, KJ. 2005. Epigentics and imprint resetting in cloned animals. In Genetics, Genomics, Proteomics and Bioinformatics. Edited by L.B. Borde, et al. London, England: John Wiley & Sons Ltd.
Eckardt, S; McLaughlin, KJ. 2009. Production of Uniparental Embryonic Stem Cell Lines. In Trends in Stem Cell Biology and Technology. Edited by H. Baharvand. New York, NY: Humana Press. 19-38.
Degrees
| 1986 | B.S., The University of Adelaide, Biology |
| 1987 | B.S.(Honors), The University of Adelaide, Reproductive Physiology |
| 1992 | Ph.D., The University of Adelaide, Obstetrics and Gynecology |
Editorial Activities
Manuscript Reviewer
| PloS One. |
| Reproduction. |
| Nature Biotechnology. |
| Nature. |
| Molecular Reproduction and Development. |
| Mechanisms in Development. |
| Genesis. |
| FEBS Journal. |
| FASEB Journal. |
| Experimental Cell Research. |
| EMBO Journal. |
| Developmental Biology. |
| Development. |
| Biology of Reproduction. |
Peer Reviewer
| Marsden Foundation. |
| The Wellcome Trust Grant Applications. |
| Australian Dairy Research Corporation Grant Applications. |
| National Science Foundation Grant Applications. |
Inventions and Patents
McLaughlin, K.J. (patent pending) P3015: Compositions for the efficient derivation of clone animals based on cell number therapy, and methods of use thereof.
McLaughlin, K.J. (patent pending) Q3602: Use of uniparental cells for therapeutic applications.
Memberships
| 1991 - present | Member. International Embryo Transfer Society |
| 1999 - present | Member. Society for the Study of Reproduction |
| 1999 - 2009 | Member. Center for Research in Reproduction and Women's Health, University of Pennsylvania |
| 1999 - 2009 | Member. Center for Developmental Biology, University of Pennsylvania |
| 1999 - 2009 | Member. Center for Animal Transgenesis and Germ Cell Research, University of Pennsylvania |
| 2003 - 2009 | Member. Biomedical Graduate Studies, Cell and Molecular Biology Program, University of Pennsylvania |
| 2004 - present | Member. International Society for Stem Cell Research |
| 2007 - 2009 | Member. Penn Institute for Regenerative Medicine |
| 2009 - present | Member. The Ohio State University Comprehensive Cancer Center |
| 2009 - present | Member. Ohio Center for Stem Cell and Regenerative Medicine |
Peer Reviewed Journal Articles
Depypere HT; McLaughlin KJ; Seamark RF; Warnes GM; Matthews CD. 1988. Comparison of zona cutting and zona drilling as techniques for assisted fertilization in the mouse. Journal Of Reproduction And Fertility. Vol. 84, no. 1 (September 1): 205.
Vanderhyden BC; McLaughlin KJ; Rutledege JM; Armstrong DT. 1989. Zona drilling increases the penetrability of rat oocytes matured in vitro. Biology Of Reproduction. Vol. 40, no. 5 (May 1): 953.
McLaughlin KJ; McLean DM; Stevens G; Ashman RA; Lewis PA; Bartsch BD; Seamark RF. 1990. Viability of one-cell bovine embryos cultured in synthetic oviduct fluid medium. Theriogenoloy. Vol. 33: 1191-99.
McLaughlin KJ; Davies L; Seamark RF. 1990. In vitro embryo culture in the production of identical merino lambs by nuclear transplantation. Reproduction, Fertility, And Development. Vol. 2, no. 6 (January 1): 619.
Walker SK; Heard TM; Verma PJ; Rogers GE; Bawden CS; Sivaprasad AV; McLaughlin KJ; Seamark RF. 1990. In vitro assessment of the viability of sheep zygotes after pronuclear microinjection. Reproduction, Fertility, And Development. Vol. 2, no. 6 (January 1): 633.
Payne D; McLaughlin KJ; Depypere HT; Kirby CA; Warnes GM; Matthews CD. 1991. Experience with zona drilling and zona cutting to improve fertilization rates of human oocytes in vitro. Human Reproduction (Oxford, England). Vol. 6, no. 3 (March 1): 423.
McLaughlin KJ; Szabó P; Haegel H; Mann JR. 1996. Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development (Cambridge, England). Vol. 122, no. 1 (January 1): 265.
Huber O; Korn R; McLaughlin J; Ohsugi M; Herrmann BG; Kemler R. 1996. Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mechanisms Of Development. Vol. 59, no. 1 (September 1): 3.
Vetter DE; Mann JR; Wangemann P; Liu J; McLaughlin KJ; Lesage F; Marcus DC; Lazdunski M; Heinemann SF; Barhanin J. 1996. Inner ear defects induced by null mutation of the isk gene. Neuron. Vol. 17, no. 6 (December 1): 1251.
Bierkamp C; Mclaughlin KJ; Schwarz H; Huber O; Kemler R. 1996. Embryonic heart and skin defects in mice lacking plakoglobin. Developmental Biology. Vol. 180, no. 2 (December 15): 780.
McLaughlin KJ; Solter D; Mann J. 1997. Developmental consequences of two paternal copies of imprinted chromosome region distal 7 in mice. Journal Of Cellular Physiology. Vol. 173, no. 2 (November 1): 242.
McLaughlin KJ; Kochanowski H; Solter D; Schwarzkopf G; Szabó PE; Mann JR. 1997. Roles of the imprinted gene Igf2 and paternal duplication of distal chromosome 7 in the perinatal abnormalities of androgenetic mouse chimeras. Development (Cambridge, England). Vol. 124, no. 23 (December 1): 4897.
Svensson K; Mattsson R; James TC; Wentzel P; Pilartz M; McLaughlin J; Miller SJ; Olsson T; Eriksson UJ; Ohlsson R. 1998. The paternal allele of the H19 gene is progressively silenced during early mouse development: the acetylation status of histones may be involved in the generation of variegated expression patterns. Development. Vol. 125, no. 1: 61-69.
Herrmann BG; Koschorz B; Wertz K; McLaughlin KJ; Kispert A. 1999. A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance. Nature. Vol. 402, no. 6758 (November 11): 141.
Oh B; Hwang S; McLaughlin J; Solter D; Knowles BB. 2000. Timely translation during the mouse oocyte-to-embryo transition. Development (Cambridge, England). Vol. 127, no. 17 (September 1): 3795.
Finkenzeller D; Fischer B; McLaughlin J; Schrewe H; Ledermann B; Zimmermann W. 2000. Trophoblast cell-specific carcinoembryonic antigen cell adhesion molecule 9 is not required for placental development or a positive outcome of allotypic pregnancies. Molecular And Cellular Biology. Vol. 20, no. 19 (October 1): 7140.
Morali OG; Jouneau A; McLaughlin KJ; Thiery JP; Larue L. 2000. IGF-II promotes mesoderm formation. Developmental Biology. Vol. 227, no. 1 (November 1): 133.
Boiani M; Eckardt S; Schöler HR; McLaughlin KJ. 2002. Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes & Development. Vol. 16, no. 10 (May 15): 1209.
Boiani M; Eckardt S; Leu NA; Schöler HR; McLaughlin KJ. 2003. Pluripotency deficit in clones overcome by clone-clone aggregation: epigenetic complementation?. The EMBO Journal. Vol. 22, no. 19 (October 1): 5304.
Eckardt S; McLaughlin KJ. 2004. Interpretation of reprogramming to predict the success of somatic cell cloning. Animal Reproduction Science. Vol. 82-83 (July 1): 97.
Kehler J; Tolkunova E; Koschorz B; Pesce M; Gentile L; Boiani M; Lomelí H; Nagy A; McLaughlin KJ; Schöler HR; Tomilin A. 2004. Oct4 is required for primordial germ cell survival. EMBO Reports. Vol. 5, no. 11 (November 1): 1078.
Kurosaka S; Eckardt S; McLaughlin KJ. 2004. Pluripotent lineage definition in bovine embryos by Oct4 transcript localization. Biology Of Reproduction. Vol. 71, no. 5 (November 1): 1578.
Eckardt S; Leu NA; Kurosaka S; McLaughlin KJ. 2005. Differential reprogramming of somatic cell nuclei after transfer into mouse cleavage stage blastomeres. Reproduction (Cambridge, England). Vol. 129, no. 5 (May 1): 547.
Yang F; De La Fuente R; Leu NA; Baumann C; McLaughlin KJ; Wang PJ. 2006. Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. The Journal Of Cell Biology. Vol. 173, no. 4 (May 22): 497.
Eckardt S; Leu NA; Bradley HL; Kato H; Bunting KD; McLaughlin KJ. 2007. Hematopoietic reconstitution with androgenetic and gynogenetic stem cells. Genes & Development. Vol. 21, no. 4 (February 15): 409.
Changolkar LN; Costanzi C; Leu NA; Chen D; McLaughlin KJ; Pehrson JR. 2007. Developmental changes in histone macroH2A1-mediated gene regulation. Molecular And Cellular Biology. Vol. 27, no. 7 (April 1): 2758.
Wuensch A; Habermann FA; Kurosaka S; Klose R; Zakhartchenko V; Reichenbach HD; Sinowatz F; McLaughlin KJ; Wolf E. 2007. Quantitative monitoring of pluripotency gene activation after somatic cloning in cattle. Biology Of Reproduction. Vol. 76, no. 6 (June 1): 983.
Kurosaka S; Eckardt S; Ealy AD; McLaughlin KJ. 2007. Regulation of blastocyst stage gene expression and outgrowth interferon tau activity of somatic cell clone aggregates. Cloning And Stem Cells. Vol. 9, no. 4 (December 1): 630.
Eckardt S; Dinger TC; Kurosaka S; Leu NA; Müller AM; McLaughlin KJ. 2008. In vivo and in vitro differentiation of uniparental embryonic stem cells into hematopoietic and neural cell types. Organogenesis. Vol. 4, no. 1 (January 1): 33.
Eckardt S; McLaughlin KJ. 2008. Transplantation of chimeric fetal liver to study hematopoiesis. Methods In Molecular Biology (Clifton, N.J.). Vol. 430. (January 1): 195.
Yang F; Eckardt S; Leu NA; McLaughlin KJ; Wang PJ. 2008. Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis. The Journal Of Cell Biology. Vol. 180, no. 4 (February 25): 673.
Yang F; Gell K; van der Heijden GW; Eckardt S; Leu NA; Page DC; Benavente R; Her C; Höög C; McLaughlin KJ; Wang PJ. 2008. Meiotic failure in male mice lacking an X-linked factor. Genes & Development. Vol. 22, no. 5 (March 1): 682.
Dinger TC; Eckardt S; Choi SW; Camarero G; Kurosaka S; Hornich V; McLaughlin KJ; Müller AM. 2008. Androgenetic embryonic stem cells form neural progenitor cells in vivo and in vitro. Stem Cells (Dayton, Ohio). Vol. 26, no. 6 (June 1): 1474.
Rai R; Wong CC; Xu T; Leu NA; Dong DW; Guo C; McLaughlin KJ; Yates JR 3rd; Kashina A. 2008. Arginyltransferase regulates alpha cardiac actin function, myofibril formation and contractility during heart development. Development (Cambridge, England). Vol. 135, no. 23 (December 1): 3881.
De Sousa PA; Gardner J; Sneddon S; Pells S; Tye BJ; Dand P; Collins DM; Stewart K; Shaw L; Przyborski S; Cooke M; McLaughlin KJ; Kimber SJ; Lieberman BA; Wilmut I; Brison DR. 2009. Clinically failed eggs as a source of normal human embryo stem cells. Stem Cell Research. Vol. 2, no. 3. (May 1): 188.
Pan J; Eckardt S; Leu NA; Buffone MG; Zhou J; Gerton GL; McLaughlin KJ; Wang PJ. 2009. Inactivation of Nxf2 causes defects in male meiosis and age-dependent depletion of spermatogonia. Developmental Biology. Vol. 330, no. 1 (June 1): 167.
Choi YH; Harding HD; Hartman DL; Obermiller AD; Kurosaka S; McLaughlin KJ; Hinrichs K. 2009. The uterine environment modulates trophectodermal POU5F1 levels in equine blastocysts. Reproduction (Cambridge, England). Vol. 138, no. 3 (September 1): 589.
Liu J; Carvalho LP; Bhattacharya S; Carbone CJ; Kumar KG; Leu NA; Yau PM; Donald RG; Weiss MJ; Baker DP; McLaughlin KJ; Scott P; Fuchs SY. 2009. Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Molecular And Cellular Biology. Vol. 29, no. 24 (December 1): 6401.
Choi SW; Eckardt S; Ahmad R; Wolber W; McLaughlin KJ; Siren AL; Muller AM. 2010. Two paternal genomes are compatible with dopaminergic in vitro and in vivo differentiation. The International Journal Of Developmental Biology. Vol. 54, no. 11-12. (January 1): 1755.
Shufaro Y; Lacham-Kaplan O; Tzuberi BZ; McLaughlin J; Trounson A; Cedar H; Reubinoff BE. 2010. Reprogramming of DNA replication timing. Stem Cells (Dayton, Ohio). Vol. 28, no. 3. (March 31): 443.
Zheng K; Xiol J; Reuter M; Eckardt S; Leu NA; McLaughlin KJ; Stark A; Sachidanandam R; Pillai RS; Wang PJ. 2010. Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 107, no. 26. (June 29): 11841.
Balbach ST; Esteves TC; Brink T; Gentile L; McLaughlin KJ; Adjaye JA; Boiani M. 2010. Governing cell lineage formation in cloned mouse embryos. Developmental Biology. Vol. 343, no. 1-2 (July 1): 71.
Espejel S; Roll GR; McLaughlin KJ; Lee AY; Zhang JY; Laird DJ; Okita K; Yamanaka S; Willenbring H. 2010. Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. The Journal Of Clinical Investigation. Vol. 120, no. 9. (September 1): 3120. (Formally Accepted)
Yang F; Cheng Y; An JY; Kwon YT; Eckardt S; Leu NA; McLaughlin KJ; Wang PJ. 2010. The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis. Plos One. Vol. 5, no. 11. (November 16): e14017.
Popkie AP; Zeidner LC; Albrecht AM; D'Ippolito A; Eckardt S; Newsom DE; Groden J; Doble BW; Aronow B; McLaughlin KJ; White P; Phiel CJ. 2010. Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. The Journal Of Biological Chemistry. Vol. 285, no. 53. (December 31): 41337.
Eckardt S; Leu NA; Yanchik A; Hatada S; Kyba M; McLaughlin KJ. 2011. Gene therapy by allele selection in a mouse model of beta-thalassemia. The Journal Of Clinical Investigation. Vol. 121, no. 2. (February 1): 623.
Maclean JA; Bettegowda A; Kim BJ; Lou CH; Yang SM; Bhardwaj A; Shanker S; Hu Z; Fan Y; Eckardt S; McLaughlin KJ; Skoultchi AI; Wilkinson MF. 2011. The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation. Molecular And Cellular Biology. Vol. 31, no. 6. (March 1): 1275.
Zhou J; Pan J; Eckardt S; Leu NA; McLaughlin KJ; Wang PJ. 2011. Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis. Molecular Reproduction And Development. Vol. 78, no. 4. (April 1): 241.
Eckardt S; McLaughlin KJ; Willenbring H. 2011. Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration. Cell Cycle (Georgetown, Tex.). Vol. 10, no. 13. (July 1): 2091.
Positions
| 1988 | Visiting Scientist, University of Western Ontario. London, ON, Canada. |
| 1991 - 1992 | Visiting Postgraduate Research Scientist, University of California, San Francisco. San Francisco, CA, United States. |
| 1992 - 1994 | Postdoctoral Scientist, City of Hope's Beckman Research Institute. Duarte, CA, United States. |
| 1994 - 1998 | Scientist, Max Planck Institute for Immunobiology. Freiburg, Germany. |
| 1998 - 1999 | Lecturer C, University of Pennsylvania, School of Veterinary Medicine, Department of Animal Biology. Philadelphia, PA, United States. |
| 1999 - 2008 | Director, University of Pennsylvania, Myrin Rodent Barrier Facility. Philadelphia, PA, United States. |
| 1999 - 2008 | Assistant Professor, University of Pennsylvania, School of Veterinary Medicine, Department of Animal Biology. Philadelphia, PA, United States. |
| 2009 - present | Principal Investigator, Research Institute at Nationwide Children's Hospital & The Ohio State University, Center for Molecular and Human Genetics. Columbus, OH, United States. |
| 2009 - present | Director, Research Institute at Nationwide Children's Hospital & The Ohio State University, The Transgenic and Embryonic Stem Cell Core. Columbus, OH, United States. |
| 2009 - present | Associate Professor, The Ohio State University College of Medicine, Department of Pediatrics. Columbus, OH, United States. |
Presentations
Other Presentations
Local
McLaughlin, KJ, Presenter. 2004. Somatic cell nuclear transfer and reprogramming. Presented at Department of Human Genetics, Emory University, Atlanta, GA.
McLaughlin, KJ, Presenter. 2006. Hematopoietic reconstitution with androgenetic and gynogenetic stem cells. Presented at Reproductive Biology Seminar Series, MD Anderson Cancer Center, Baylor College of Medicine, Houston TX.
McLaughlin, KJ, Presenter. 2006. Therapeutic potential of uniparental cells. Presented at Department of Veterinary and Animal Science, University of Massachusetts, Amherst MA.
McLaughlin, KJ, Presenter. 2007. Therapeutic application of uniparental embryonic stem cells. Presented at Stem Cell Seminar Series, University of California, San Francisco CA.
McLaughlin, KJ, Presenter. 2007. Therapeutic approaches using uniparental (embryonic) stem cells. Presented at The Department of Cell Biology and Neuroscience Stem Cell Seminar Series, University of California, Riverside CA.
McLaughlin, KJ, Presenter. 2007. Tissue and organ regeneration in adult mice with uniparenteral embryonic stem cell derivatives. Presented at The Department of Biochemistry, University of Adelaide, Australia.
McLaughlin, KJ, Presenter. 2007. Uniparental cells: Therapeutic potential. Presented at Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas TX.
McLaughlin, KJ, Presenter. 2008. Models of autologous transplantation using uniparental cells. Presented at College of Veterinary Medicine, Texas A&M University.
McLaughlin, KJ, Presenter. 2008. Tissue and organ regeneration in adult mice with uniparental embryonic stem cell derivatives. Presented at The Institute for Regenerative Medicine, University of Pennyslvania.
McLaughlin, KJ, Presenter. 2008. Uniparental cells and genetic correction of disease. Presented at Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, LA.
McLaughlin, KJ, Presenter. 2009. Pluripotent cells for autologous transplantation therapies: Uniparental stem cells. Presented at The Ohio State University Comprehensive Cancer Center (OSUCCC) Bi-Annual Retreat, Columbus, OH.
McLaughlin, KJ, Presenter. 2009. Transplantation models for pluripotent stem cells and how to make money using the Transgenic Mouse core. Presented at The Research Institute at Nationwide Children's Hospital Weekly Seminar Series, Columbus, OH.
McLaughlin, KJ, Presenter. 2010. Autologous pluripotent stem cell transplantation. Presented at The Ohio State University Department of Veterinary Services, Columbus OH.
McLaughlin, KJ, Presenter. 2011. Animal Model Development. Presented at Nationwide Children's Hospital and Battelle Memorial Institute Collaboration Workshop. Columbus, OH.
National
McLaughlin, KJ, Presenter. 2001. Visualizing reprogramming of Oct4 in mouse clones. Presented at Banbury Meeting: Stability and Reversal of the Differentiated State, Cold Harbor Spring Laboratories.
McLaughlin, KJ, Presenter. 2002. Disruption of pluripotency in mouse clones. Presented at Keystone Symposium Stem Cells: Origins, Fate and Function, Keystone, CO.
McLaughlin, KJ, Presenter. 2002. Pluripotency in mouse somatic cell clones. Presented at Gordon Conference: Embryogenesis and Gametogenesis, Connecticut College.
McLaughlin, KJ, Presenter. 2005. Hematopoietic reconstitution with uniparental cells. Presented at International Society for Stem Cell Research Annual Meeting, San Francisco.
McLaughlin, KJ, Presenter. 2005. What stem cells can do in animals and people, now, and in the future? Presented at Bioethics Panel, Bio2005 Conference, Philadelphia, PA.
International
McLaughlin, KJ, Presenter. 2004. Interpretation of reprogramming in somatic cell nuclear transfer. Presented at International Congress of Animal Reproduction, Porto Seguro, Brazil.
McLaughlin, KJ, Presenter. 2007. Hematopoietic reconstitution iwth androgenetic and gynogenetic stem cells. Presented at Department of Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
McLaughlin, KJ, Presenter. 2007. Parthenogenetic ES cells form transplantable hematopoietic progenitor cells in vitro. Presented at International Society for Stem Cell Research Annual Meeting, Cairns, Australia.
McLaughlin, KJ, Presenter. 2007. What is the stem cell potential of uniparental cells? Presented at Down Under Embryo Symposium, Gold Coast, Australia.
McLaughlin, KJ, Presenter. 2011. Approaches for generating and validating regenerative capacity of patient derived pluripotent stem cells. Presented at University of Calgary, School of Veterinary Medicine. Calgary, Alberta, Canada.
Professional Activities
Conference Participation
| 2004 | Biomedical Postdoctoral Research Symposium. Faculty Judge. University of Pennyslvania. |
| 2005 | Gene Expression. Section Editor. International Embryo Transfer Society (IETS). Copenhagen, Denmark. |
| 2006 | Session IV: Epigentics and Placental Function. Session Chair. International Embryo Transfer Society Meeting. Orlando, FL. |
| 2007 | Penn Stem Cell Workshop, New Bolton Center. Organizer. |
Undergrad., Grad. and Prof. Courses Taught
1992. Cold Spring Harbor Laboratory, Cold Spring Harbor Mouse Course (Laboratory Instructor).
1997. University of Heidelberg, EMBO Mammalian Development Course (Laboratory Instructor).
2000. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2000. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2001. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2001. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2001. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2002. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2002. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2002. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2003. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2003. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2003. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2003. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program. Experimental Principles in Molecular Biology (Lecturer).
2004. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2004. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2004. University of Pennsylvania, School of Veterinary Medicine. Seminars in Developmental Biology (Faculty Mentor) VANB633.
2004. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2005. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2005. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2005. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2005. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2005. University of Pennsylvania, School of Veterinary Medicine. Seminars in Developmental Biology (Faculty Mentor) VANB633.
2005. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program. Engineering Entrepreneurship I (Faculty Mentor) EAS445/545.
2006. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2006. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2006. University of Pennsylvania, School of Veterinary Medicine. Seminars in Developmental Biology (Faculty Mentor) VANB633.
2006. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2007. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2007. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2007. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
2007. University of Pennsylvania, School of Veterinary Medicine. Seminars in Developmental Biology (Faculty Mentor) VANB633.
2007. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program. Bioethics Workshop (Faculty Mentor).
2008. University of Pennsylvania, School of Veterinary Medicine. Developmental Biology: Stem Cells, Fertilization and Preimplantation Development (Lecturer and Laboratory Instructor) VANB603.
2008. University of Pennsylvania, School of Veterinary Medicine. Histology: Male and Female Reproductive Tract (Lecturer and Laboratory Instructor) VANB602.
2008. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program. Bioethics Workshop (Faculty Mentor).
2008. University of Pennsylvania, Biomedical Graduate Studies, Cell and Molecular Biology Program (Faculty Mentor).
Summer 2011. The College of Medicine COLMBUS, Integrated Biomedical Science. Individual Studies 793 . 15 credit hours